Vaccine Diagnosis of Gonorrhea

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Methodofluorescence for the Diagnosis of Gonorrhea

1. A direct fluorescent antibody (F.A.) tech­nique for diagnosis of Gonococci is de­scribed. 2. The results of applying F.A. method in the 270 female cases are presented and compared with the conventional method find­ings. 3. 220 cases were diagnosed by one or more methods at the first examinations. F .A. tests alone were positive in 44 ,eases and .F .A. direct diagnosis was made in a tot...

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Enzyme immunoassay for diagnosis of gonorrhea.

An enzyme immunoassay (EIA; Gonozyme [Abbott Laboratories]) for gonococcal antigen was assessed for the rapid diagnosis of gonorrhea. Patients attending two sexually transmitted disease clinics were tested by EIA and culture on Thayer-Martin medium. EIA was highly effective in detecting gonococcal infection among symptomatic men, with 70 of 75 (93.3%) culture-positive men having positive tests ...

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Antigen detection for the diagnosis of gonorrhea.

We compared the diagnostic value of an enzyme immunoassay method for detection of gonococcal antigen in genital secretions with culture results and direct Gram stain for Neisseria gonorrhoeae in 1,171 men and 723 women attending a sexually transmitted disease clinic. When compared with culture results in men, the immunoassay provided a sensitivity of 94% and a specificity of 98% and was essenti...

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Fluorescent antibody test for the serological diagnosis of gonorrhea.

An indirect fluorescent antibody technique has been developed for the serological diagnosis of gonorrhea. The selected strain(s) of Neisseria gonorrhoeae possesses a heat-labile surface antigen (L-antigen). Sera are diluted 1:10, and an aliquot is hear inactivated at 59 C for 30 min. The treated and untreated aliquots are then examined for human immunoglobulin G anti-L-antigen. In a prelimiary ...

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ژورنال

عنوان ژورنال: The American Journal of the Medical Sciences

سال: 1912

ISSN: 0002-9629

DOI: 10.1097/00000441-191212000-00064